The Potential For Improved Inhalation Technique With Duoresp® Spiromax® (Budesonide + Formoterol Fumarate Dihydrate) Compared With Commonly Prescribed Dry Powder Inhalers For The Management Of Asthma And Chronic Obstructive Pulmonary Disease In Spain: Estimated Impact On Number And Cost Of Unscheduled Healthcare Events.
نویسندگان
چکیده
• Asthma and chronic obstructive pulmonary disease (COPD) are common respiratory conditions that represent a considerable cost burden to the Spanish healthcare system1. • Symbicort® Turbuhaler® (budesonide + formoterol fumarate dihydrate) and Seretide® Accuhaler® (fluticasone propionate + salmeterol) are commonly used dry powder inhalers (DPIs) in Spain, and can be difficult for patients to train with and use2–7. • Difficult to use inhalers can lead to patients demonstrating poor inhalation technique, defined as making at least one critical inhaler error – which drastically reduces, or prevents entirely, deposition of medicine in the lungs8. • Poor inhalation technique contributes to the economic burden of disease management by increasing the risk of unscheduled healthcare events, and therefore costs associated with event management, compared with patients who demonstrate good inhalation technique9. • DuoResp® Spiromax® is a new budesonide + formoterol fixed dose combination (FDC) DPI indicated in Europe for use in the same adult asthma and COPD population as the equivalent delivered doses of Symbicort® Turbuhaler®10. • DuoResp® Spiromax® was designed to address many training and usability issues associated with commonly used DPIs, and has the potential to improve inhalation technique.
منابع مشابه
The economic burden of asthma and chronic obstructive pulmonary disease and the impact of poor inhalation technique with commonly prescribed dry powder inhalers in three European countries
BACKGROUND Asthma and chronic obstructive pulmonary disease (COPD) are common chronic inflammatory respiratory diseases, which impose a substantial burden on healthcare systems and society. Fixed-dose combinations (FDCs) of inhaled corticosteroids (ICS) and long-acting β2 agonists (LABA), often administered using dry powder inhalers (DPIs), are frequently prescribed to control persistent asthma...
متن کاملEstimating the economic consequences of an increased medication adherence due to a potential improvement in the inhaler technique with Spiromax® compared with Turbuhaler® in patients with moderate-to-severe chronic obstructive pulmonary disease in Spain
OBJECTIVE The objective of this study was to estimate the economic impact of the introduction of DuoResp® Spiromax®, budesonide/formoterol fixed-dose combination (FDC), focusing on an increase in medication adherence due to an enhancement of the inhalation technique for the treatment of COPD patients in Spain and 5 regions including Andalusia, Catalonia, Galicia, Madrid, and Valencia. METHODS...
متن کاملA budget impact analysis of Spiromax® compared with Turbuhaler® for the treatment of moderate to severe asthma: a potential improvement in the inhalation technique to strengthen medication adherence could represent savings for the Spanish Healthcare System and five Spanish regions
OBJECTIVE To assess the economic impact of the introduction of DuoResp(®) Spiromax(®) by focusing on a potential improvement in the inhalation technique to strengthen medication adherence for the treatment of moderate to severe asthmatics in Spain and five Spanish regions including Andalusia, Catalonia, Galicia, Madrid, and Valencia. METHODS A 4-year budget impact model was developed for the ...
متن کاملSpiromax, a New Dry Powder Inhaler: Dose Consistency under Simulated Real-World Conditions
BACKGROUND Spiromax(®) is a novel dry powder inhaler for patients with asthma or chronic obstructive pulmonary disease (COPD). The studies presented here provide further data on attributes (in vitro dosing consistency with budesonide-formoterol (DuoResp) Spiromax; flow rates through empty versions of the Spiromax and Turbuhaler inhaler) of importance to patients with asthma or COPD. METHODS D...
متن کاملInhalation characteristics of asthma patients, COPD patients and healthy volunteers with the Spiromax® and Turbuhaler® devices: a randomised, cross-over study
BACKGROUND Spiromax® is a novel dry-powder inhaler containing formulations of budesonide plus formoterol (BF). The device is intended to provide dose equivalence with enhanced user-friendliness compared to BF Turbuhaler® in asthma and chronic obstructive pulmonary disease (COPD). The present study was performed to compare inhalation parameters with empty versions of the two devices, and to inve...
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ورودعنوان ژورنال:
- Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research
دوره 18 7 شماره
صفحات -
تاریخ انتشار 2015